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25-May-2019 23:21

The recessive gene for Canavan, as for the better-known Tay-Sachs disease, crops up most often in the Ashkenazi Jewish population, and Gabi and Zohar found that they were both carriers—meaning that any children they conceived would have a one-in-four chance of being born with the disease. Until then, the Ilinetskys had thought of themselves as a couple with two children, one with special needs and one without.With Yoel, some signs had always been there: his precocious rolling, for example, came from spastic tensing in his muscles. Now they were facing the terminal brain decay of both kids.Before long, his son did the most precocious thing an infant can and rolled over.It was while watching Yoel roll on the floor one day, chatting to him as if to a middle-aged man, that Zohar noticed a fleeting peculiarity in his son’s eyes, which seemed to flicker back and forth, like the pupils of somebody trying to read a subway-station sign through the window of a moving train.

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We knew we were going to have children.”To their delight, Gabi gave birth to twins: a boy, a girl. Zohar, who does not believe in baby talk, had long, one-sided conversations with his newborn children, in Hebrew; he thought that they could understand him, or soon would.But the endeavor, like sharing photographs and shopping, has gained form and focus in an age of digital connection.On the Internet, crowdfunding is distinguished by its scale.Leone’s team aims to replace the mutated gene in Canavan patients with a normal version, packaged in a special virus that “infects” primarily white-matter cells. Frustrated with the system, the Ilinetskys decided to go outside it.The procedure, one of several gene-therapy protocols in development for Canavan patients, has been effective in rodents; it is awaiting funding and F. “We thought maybe we could buy a few thousand lottery tickets,” Zohar said, grimly.

We knew we were going to have children.”To their delight, Gabi gave birth to twins: a boy, a girl. Zohar, who does not believe in baby talk, had long, one-sided conversations with his newborn children, in Hebrew; he thought that they could understand him, or soon would.But the endeavor, like sharing photographs and shopping, has gained form and focus in an age of digital connection.On the Internet, crowdfunding is distinguished by its scale.Leone’s team aims to replace the mutated gene in Canavan patients with a normal version, packaged in a special virus that “infects” primarily white-matter cells. Frustrated with the system, the Ilinetskys decided to go outside it.The procedure, one of several gene-therapy protocols in development for Canavan patients, has been effective in rodents; it is awaiting funding and F. “We thought maybe we could buy a few thousand lottery tickets,” Zohar said, grimly.Through their own research, the Ilinetskys found a physical-therapy program called Neuro Movement, which purports to cultivate brain plasticity.